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[Usefulness of antidepressants in anxiety disorders]
1Service de psychiatrie et de psychologie médicale, CHU SartTilman, B-4000 Lieège. marc.ansseau@chu.ulg.ac.be
Abstract:
This article deals with four anxiety disorders particularly frequent in the population as well as in general practice: panic disorder, specific phobias, social phobia and generalized anxiety. After a brief description of their clinical characteristics and prevalence, it provides the general principles of treatment and mainly the specific role of antidepressants. Finally, for each disorder, a treatment algorithm based on available guidelines is proposed. Schematically, antidepressants and particularly selective serotonin reuptake inhibitors exhibit a usefulness assessed as important in panic disorder, moderate in generalized anxiety, weak in social phobia and absent in specific phobias.
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Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic circuitry.
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Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs
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Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.