Inheritance of some electrophoretic phenotypes of human hair

Four isokeratin patterns were demonstrated by means of one-dimensional SDS electrophoresis of low sulfur proteins in human hair. The phenotypes had the following frequencies: K1 = 69.70%, K1m = 18.18%, K3 = 9.09%, K3m = 3.03%. Pedigree analysis and evaluation of observed and expected frequencies of the phenotypes gave rise to the conclusion that the phenotypes are controlled by genes of two independent autosomal loci K and m. We believe that *K3 and *m are dominant, whereas *K1 and *non-m are recessive.