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Zebrafish Whole Mount High-Resolution Double Fluorescent In Situ Hybridization
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Fluorescence in situ hybridization using the subtelomeric 11q probe as a diagnostic tool for congenital

G Göhring, C Hanke, C Kratz

    Annals of Hematology
    |September 16, 2006
    PubMed
    Abstract

    No abstract available in PubMed .

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    Fluorescence in situ hybridization, or FISH, was developed in the early 1980s and has quickly become one of the most widely used techniques in cytogenetics. Labeled probes are used to bind complementary DNA or RNA sequences on a chromosome or in a region within a cell. Earlier, the probes could only be obtained by cloning or reverse transcription of a DNA template. Currently, the probe oligonucleotides can be synthesized synthetically. Additionally, with the advancement of optical techniques,...

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