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Updated: Jul 20, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Meningiomas with skull bone involvement]
Z Novák1, J Chrastina, E Lzicarová
1Neurochirurgická klinika LF MU FN u sv. Anny, Brnĕ. zdenek.novak@fnusa.cz
Abstract:
One of factors responsible for meningioma recurrencies is tumorous involvement of calvarial and basal bone structures. Primary intraosseous meningiomas should be distinguished from secondary involvement in prevailing intracranial tumor and hyperostotic reactive changes. The paper is based on prospective study of 167 patient operated on for intracranial meningioma. Based on clinical investigation, radiological and intraoperative data bone invasion was suspected in 20 patients and histologically confirmed in 17. In 14 patients bone involvement was secondary, meningothelial hamartoma was described in one patient and in 2 patient primary intraosseous meningioma was found. Prevalence of tumors to periorbital area and bone sutures is confirmed. Neuronavigation is used to optimise tumor resection and limit the risk for neurovascular structures. Results were good in 87.5% of patients and poor in 12.5% of patients (extent of tumor and general condition). Discussion provides analysis of intraosseous meningiomas formation, pathological classification (Lang), causes of bone invasion and surgical possibilities. It is necessary to undeline the problems of intraosseous meningiomas both from the aspects of diagnosis and subsequent treatment.
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