Related Experiment Video
Updated: Aug 13, 2026

Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis
Published on: August 2, 2013
[The diagnosis of ghost cell glaucoma with methyl violet stain]
1Lü Lin Ophthalmic Hospital, Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, Guang dong Province.
Abstract:
The diagnosis in 30 cases of ghost cell glaucoma was confirmed by the method of 1% methyl violet staining, which was simple, convenient and pathognomonic. The authors believed that ghost cells could develop both in the anterior chamber and in the vitreous. Since the hypotensive effect was marked, treatment should not be neglected even for cases with no light perception.
Insights
Ghost cell glaucoma diagnosis is reliably confirmed using simple 1% methyl violet staining. Prompt treatment is crucial for this condition, even in advanced cases with no light perception.
Area of Science:
- Ophthalmology
- Pathology
Context:
- Ghost cell glaucoma is a severe form of secondary glaucoma.
- Diagnosis can be challenging, requiring specific pathological markers.
Purpose:
- To evaluate the efficacy of 1% methyl violet staining for diagnosing ghost cell glaucoma.
- To emphasize the importance of treatment regardless of visual prognosis.
Summary:
- Diagnosis of 30 ghost cell glaucoma cases was confirmed using 1% methyl violet staining.
- This staining method is simple, convenient, and pathognomonic.
- Ghost cells can manifest in both the anterior chamber and vitreous.
Impact:
- 1% methyl violet staining offers a definitive diagnostic tool for ghost cell glaucoma.
- Early and aggressive treatment is vital due to significant hypotensive effects, even in eyes with no light perception.

