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Updated: Jul 20, 2026

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
3D-FLAIR magnetic resonance imaging in the evaluation of mumps deafness
Hironao Otake1, Makoto Sugiura, Shinji Naganawa
1Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, 65, Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. hiro07@med.nagoya-u.ac.jp
Abstract:
A 6-year-old boy suffered acute profound right side deafness after his classmates had mumps. Although his salivary glands were not swollen, he had high levels of anti-mumps IgM and IgG antibodies. The three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) procedure applied to magnetic resonance imaging (MRI) showed high signals in the right cochlea and vestibule. This indicated hemorrhage or a high concentration of protein in the right inner ear. This is the first case demonstrating a high 3D-FLAIR MRI signal of the inner ear in a patient with mumps deafness. Our findings suggest that 3D-FLAIR MRI may help to identify and define labyrinthitis in mumps deafness.
Insights
Mumps can cause sudden, profound deafness. This case shows three-dimensional FLAIR MRI revealing inner ear inflammation, aiding diagnosis of mumps-related hearing loss.
Area of Science:
- Otolaryngology
- Neurology
- Radiology
Background:
- Mumps virus infection can lead to sensorineural hearing loss.
- Diagnosis of mumps-induced deafness can be challenging, especially without parotitis.
Observation:
- A 6-year-old boy presented with acute, profound right-sided deafness following mumps exposure.
- He exhibited elevated anti-mumps IgM and IgG antibodies but no salivary gland swelling.
- Magnetic resonance imaging (MRI) using a three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence revealed high signals in the right inner ear.
Findings:
- The high 3D-FLAIR MRI signals in the cochlea and vestibule suggest inner ear hemorrhage or proteinaceous fluid.
- This is the first reported case of characteristic 3D-FLAIR findings in mumps-associated deafness.
- The findings correlate with labyrinthitis, an inflammation of the inner ear.
Implications:
- Three-dimensional FLAIR MRI may serve as a valuable tool for diagnosing labyrinthitis in cases of mumps deafness.
- This imaging technique could improve the identification and understanding of inner ear complications from mumps virus.
- Further research may elucidate the specific pathological changes indicated by 3D-FLAIR signals in mumps labyrinthitis.
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