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Prone breast irradiation for pendulous breasts.

Jeroen Buijsen1, Jos J Jager, Janneke Bovendeerd

  • 1Department of Radiation Oncology (Maastro Clinic), GROW, University Hospital Maastricht, Maastricht, The Netherlands. jeroen.buijsen@maastro.nl

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
|September 19, 2006
PubMed
Summary

For patients with pendulous breasts, the prone position improves dose homogeneity and lowers organ-at-risk doses in radiation therapy. However, this comes at the expense of reduced planning target volume coverage with current techniques.

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Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Radiotherapy Planning

Background:

  • Pendulous breasts present unique challenges in radiotherapy positioning.
  • Optimizing dose distribution while minimizing dose to organs at risk is crucial for effective cancer treatment.
  • Comparing prone and supine positions is essential for patient positioning strategies.

Purpose of the Study:

  • To quantify dose differences in organs at risk for patients with pendulous breasts.
  • To compare planning target volume (PTV) coverage and dose homogeneity between prone and supine positions.
  • To evaluate the trade-offs in radiotherapy planning for pendulous breasts based on patient position.

Main Methods:

  • Computed tomography (CT)-based treatment planning was performed for 10 patients in both prone and supine positions.
  • Dose data for organs at risk and PTV coverage were collected and analyzed.
  • Dose homogeneity was assessed using established metrics.

Main Results:

  • The prone position demonstrated superior dose homogeneity compared to the supine position.
  • Doses to organs at risk were significantly lower in the prone position.
  • A reduction in PTV coverage was observed in the prone position with the current technique.

Conclusions:

  • The prone position offers potential benefits for dose distribution in radiotherapy for pendulous breasts.
  • Further technical advancements may be needed to overcome the reduced PTV coverage in the prone position.
  • Patient positioning in prone may be advantageous for reducing radiation-induced toxicity in specific patient populations.