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Local microwave hyperthermia of benign prostatic hyperplasia
W L Strohmaier1, K H Bichler, S H Flüchter
1Department of Urology, University of Tübingen Medical School, Federal Republic of Germany.
The Journal of Urology
|October 1, 1990
Summary
Local microwave hyperthermia shows limited effectiveness for benign prostatic hyperplasia (BPH). This study found minimal improvement in voiding parameters and prostate size, suggesting it
Area of Science:
- Urology
- Medical Physics
Background:
- Benign prostatic hyperplasia (BPH) is a common condition in aging men.
- Hyperthermia has emerged as a potential treatment modality for BPH.
- Objective voiding parameters for BPH patients undergoing hyperthermia require further investigation.
Purpose of the Study:
- To evaluate the efficacy of local microwave hyperthermia in treating benign prostatic hyperplasia.
- To assess changes in objective voiding parameters and prostate size following hyperthermia therapy.
Main Methods:
- A phase II study involving 30 patients with BPH.
- Transrectal microwave hyperthermia (915 MHz) applied over 8 sessions.
- Assessment of transrectal ultrasound, prostate volume, urinary flow rate, and residual volume before and after treatment.
Main Results:
- Only 2 out of 28 evaluable patients showed relevant improvement.
- No significant changes were observed in voiding parameters or prostate size.
- The treatment success rate was 7.1%, which is lower than spontaneous regression rates.
Conclusions:
- Local microwave hyperthermia is not an effective treatment for benign prostatic hyperplasia.
- Hyperthermia's efficacy is comparable to or worse than established treatments like transurethral resection.
- Further research may be needed to explore alternative hyperthermia parameters or patient selection criteria.