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A failure to launch: fuelling cytokine secretion in iNKT cells
1Howard Hughes Medical Institute, Department of Medicine and Microbiology/Immunology, University of California, San Francisco, San Francisco, California 94143-0795, USA.
Immunity
|September 19, 2006
Abstract:
In this issue of Immunity, Bezbradica et al., (2006) uncover an unsuspected role for the cytokine GM-CSF in the thymic development of invariant NKT cells, a role that licenses these cells to secrete effector cytokines upon activation in the periphery.
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