Related Experiment Video
Updated: Jul 20, 2026
Postoperative Ileus Murine Model
Published on: July 12, 2024
Hemorrhoids: an experimental model in monkeys
1Department of Surgery, Federal University of São Paulo (UNIFESP), São Paulo, Brazil. helio@plapler.com.br
Purpose:
Hemorrhoids are a matter of concern due to a painful outcome. We describe a simple, easy and reliable experimental model to produce hemorrhoids in monkeys.
Methods:
14 monkeys (Cebus apella) were used. After general anesthesia, hemorrhoids were induced by ligation of the inferior hemorrhoidal vein, which is very alike to humans. The vein was located through a perianal incision, dissected and ligated with a 3-0 vicryl. The skin was sutured with a 4-0 catgut thread. Animals were kept in appropriate cages and evaluated daily.
Results:
Nine days later there were hemorrhoidal piles in the anus in fifty percent (50%) of the animals. Outcome was unremarkable. There was no bleeding and all animals showed no signs of pain or suffering.
Conclusion:
This is an affordable and reliable experimental model to induce hemorrhoids for experimental studies.
