Related Experiment Video
Updated: Jul 20, 2026
05:36
Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis
Published on: October 4, 2024
Challenges of conducting a placebo-controlled trial for dysmenorrhea in adolescents
Anne R Davis1, Lauren M Osborne, Katharine J O'Connell
1Department of Obstetrics and Gynecology, Columbia University, New York, New York 10032, USA. ard4@columbia.edu
Abstract:
We recruited adolescents to study oral contraceptives versus placebo for dysmenorrhea. We anticipated high discontinuation and concerns about safety, side effects, and sexual behavior. Treatment discontinuation (11%) and loss to follow-up (1%) were lower than expected. The most common reason for nonenrollment was logistical issues (63%). Most participants remained abstinent.