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Related Experiment Video

Updated: Jul 19, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

Technique survival with Serratia peritonitis.

Swapnil Hiremath1, Mohan Biyani

  • 1Division of Nephrology, Kidney Research Center, Ottawa Health Research Institute, Ontario, Canada. shiremath@ottawahospital.on.ca

Advances in Peritoneal Dialysis. Conference on Peritoneal Dialysis
|September 21, 2006
PubMed
Summary

Peritonitis from Serratia bacteria in peritoneal dialysis (PD) patients leads to technique failure in nearly one-third of cases. Prompt antibiotic treatment, especially with aminoglycosides, may improve outcomes for Serratia peritonitis.

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Last Updated: Jul 19, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Peritoneal Dialysis

Background:

  • Peritonitis is a major cause of peritoneal dialysis (PD) technique failure.
  • Serratia species infections have been linked to poor PD outcomes.

Purpose of the Study:

  • To investigate the outcomes of Serratia peritonitis in PD patients.
  • To evaluate the effectiveness of different antibiotic regimens for Serratia peritonitis.

Main Methods:

  • Retrospective review of PD patients with peritonitis from 1996-2003.
  • Analysis of patient demographics, PD characteristics, and treatment outcomes for Serratia infections.
  • Comparison of technique survival rates based on initial antibiotic regimens.

Main Results:

  • Serratia peritonitis occurred in 16 episodes (3.68%) among 12 PD patients.
  • Technique survival for Serratia peritonitis was 68.8%, with 4 catheter removals and 1 death due to sepsis.
  • Initial antibiotic regimens including an aminoglycoside showed higher technique survival (80%) compared to cefazolin-ceftazidime (60%).

Conclusions:

  • Serratia peritonitis is associated with a significant risk of PD technique failure.
  • Aminoglycoside-containing antibiotic regimens may improve technique survival in Serratia peritonitis.
  • Further research into optimal treatment strategies for Serratia peritonitis is warranted.