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The cystic fibrosis gene: isolation and significance
F S Collins1, J R Riordan, L C Tsui
1University of Michigan.
Hospital Practice (Office Ed.)
|October 15, 1990
Abstract:
The identification and cloning of the CF gene, which codes for a membrane protein that appears to regulate transmembrane ion transport, may lead to an understanding of the basic defect in the disease and to more effective treatment. More broadly, the cloning of the CF gene provides a fast start in the international effort to clone and map the entire human genome.