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Related Experiment Video

Updated: Jul 19, 2026

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

The Oregon depo-Provera program: a five-year follow-up.

Barry M Maletzky¹, Arthur Tolan, Bentson McFarland

¹Oregon Health Sciences University, USA. marbar@easystreet.com

Sexual Abuse : a Journal of Research and Treatment

|September 22, 2006

Summary

Medication with medroxyprogesterone acetate (MPA) was evaluated in sexual offenders. Men receiving MPA had no new sexual offenses, fewer overall offenses, and violations compared to those not receiving it.

Related Experiment Videos

Last Updated: Jul 19, 2026

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

Area of Science:

Forensic Psychiatry
Clinical Psychology
Pharmacology

Background:

Oregon House Bill 2500 (1999) mandated evaluations for selected sexual offenders prior to release.
The bill aimed to assess the need for medroxyprogesterone acetate (MPA) treatment to mitigate recidivism risk.

Purpose of the Study:

To review the outcomes of the first 275 men evaluated under Oregon's MPA program (2000-2004).
To compare recidivism rates and officer-reported outcomes among men who received MPA, were recommended but did not receive MPA, and were not recommended for MPA.

Main Methods:

Retrospective review of 275 male offenders evaluated between 2000 and 2004.
Data collection on diagnoses, MPA treatment status, recidivism (sexual and non-sexual offenses, parole violations, reincarcerations), employment, and officer assessments.

Main Results:

Men who received MPA committed no new sexual offenses and had significantly fewer overall offenses and violations.
Among men recommended but not receiving MPA, nearly one-third committed new offenses, with 60% being sexual in nature.
Significant differences in outcomes were observed across the three treatment groups.

Conclusions:

Anti-androgenic medication like MPA may be a valuable adjunct to cognitive and behavioral programs for selected sexual offenders.
Findings support the use of MPA as a time-limited treatment to reduce sexual recidivism.
The study suggests broader implementation of MPA as an adjunctive treatment strategy.