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Updated: Jul 19, 2026

A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
Published on: July 18, 2025
Follow-up of early unilateral nephrectomy for hypertension
Shivaram Hegde1, Malcolm G Coulthard
1Department of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle-upon-Tyne NE1 4LP, UK.
Abstract:
Early unilateral nephrectomy was carried out in four young children with unilateral renovascular disease, a poorly functioning kidney and hypertension. At follow-up 5-16 years later all showed normal growth, blood pressure and renal function, and only one child had low-grade albuminuria. Unilateral nephrectomy seems to be a safe and effective alternative to long-term hypotensive treatment.
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