Giant coronary artery aneurysm causing superior vena cava syndrome and congestive heart failure
Gautam Kumar1, Barry L Karon, William D Edwards
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Insights
Giant coronary artery aneurysms, rare dilations of heart arteries, can cause serious conditions like superior vena cava syndrome and heart failure. This case highlights their potential for severe complications.
Area of Science:
- Cardiology
- Vascular Medicine
- Radiology
Background:
- Coronary artery aneurysms (CAAs) are localized dilations >1.5 times adjacent segments.
- In adults, CAAs are typically atherosclerotic and often asymptomatic.
- Giant CAAs are particularly rare and their clinical manifestations are not well-documented.
Observation:
- This report details the first case of a giant coronary artery aneurysm causing superior vena cava syndrome and heart failure.
- Diagnostic imaging included chest x-ray, echocardiography, CT, and coronary angiography.
- Findings revealed cardiomegaly and a mass consistent with a giant CAA.
Findings:
- A giant coronary artery aneurysm was identified as the cause of superior vena cava syndrome.
- The aneurysm's mass effect led to significant cardiac compromise and heart failure.
- Diagnostic modalities confirmed the aneurysm's size and location.
Implications:
- Giant coronary artery aneurysms can present with life-threatening complications, including superior vena cava syndrome.
- Early diagnosis and recognition of CAA-related complications are crucial for patient management.
- This case expands the known clinical spectrum of giant coronary artery aneurysms.
Abstract:
Coronary artery aneurysms are defined as localized coronary artery dilations >1.5 times the diameter of the adjacent segments. In adults, they are commonly of atherosclerotic origin and are usually asymptomatic. This is the first case report of a coronary artery aneurysm causing superior vena cava syndrome and heart failure. Chest x-ray showed cardiomegaly, and transthoracic echocardiography showed a mass that was confirmed by transesophageal echocardiography, computed tomography, and coronary angiography. In conclusion, giant coronary artery aneurysms can cause superior vena cava syndrome.
Related Concept Videos
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Heart Failure III: Clinical Manifestations
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the middle...
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Cardiomyopathy II: Dilated Cardiomyopathy
Mitral Regurgitation I: Introduction


