Related Experiment Video
Updated: Jul 19, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Periodontal disease and systemic conditions: a bidirectional relationship
1Boston University Goldman School of Dental Medicine, Department of Periodontology and Oral Biology, Boston, MA, USA.
Odontology
|September 26, 2006
Summary
Oral health is linked to overall systemic health. Treating periodontal disease may improve related systemic conditions like cardiovascular disease and diabetes.
Area of Science:
- Oral Health and Systemic Disease Linkages
- Interdisciplinary Medicine
Background:
- Traditionally, medicine and dentistry have operated in separate specialties.
- Emerging evidence highlights the connection between oral health and systemic well-being.
- Periodontal disease is increasingly recognized as a significant indicator of systemic health.
Purpose of the Study:
- To explore the etiological and pathological links between periodontal disease and systemic conditions.
- To emphasize the closing gap between dental and allopathic medicine.
- To highlight the potential for treating periodontal disease to improve systemic health.
Main Methods:
- Review of recent findings and studies.
- Analysis of etiological and pathological associations.
- Synthesis of evidence linking periodontal disease to systemic conditions.
Main Results:
- Strong evidence supports associations between periodontal disease and cardiovascular disease, type 2 diabetes mellitus, adverse pregnancy outcomes, and osteoporosis.
- Advances have been made in understanding the links between this chronic inflammatory dental disease and systemic illnesses.
- The gap between allopathic and dental medicine is narrowing.
Conclusions:
- Treating periodontal infection holds promise for ameliorating associated systemic illnesses.
- Further research is crucial to uncover more correlations between periodontal and systemic diseases.
- Focusing on the positive impact of periodontal disease treatment on systemic health is essential.
Related Concept Videos
01:27The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
01:28Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
01:15Teeth
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
01:18Dysbiosis of the Gut Microbiota
The human gut microbiome includes a diverse array of microbial species, including beneficial commensals and opportunistic pathogens, which interact to support host health. These microbes contribute to essential functions such as nutrient metabolism, immune system modulation, and maintenance of intestinal barrier integrity. However, disruptions to this equilibrium—referred to as dysbiosis—can have widespread physiological consequences.Dysbiosis is often characterized by reduced microbial...
01:21Tooth Anatomy
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD: