Related Experiment Video
Updated: Jul 19, 2026

The Establishment of Calvarial Suture-Bony Composite Defects in Rats: A Standardized Model for Suture-Regenerative Therapy Investigation
Published on: May 10, 2024
[Use of calcium sulfate as internal matrix to repair furcal perforations]
Ling Zou1, Shi-Hai Yin, Jun Liu
1Key. Laboratory of Oral Biomedical Engineering, Ministry of Education, Sichuan University, Chengdu 610041, China.
Objective:
To evaluate the effect of internal matrix on sealing ability and furcal appearance of perforations repair with amalgam and resin.
Methods:
Perforations created in the pulpal floor of human extracted molars were repaired as follows: Amalgam, amalgam plus calcium sulfate, light-cured resin, and resin plus calcium sulfate (15 teeth/group). The furcal appearance of samples was evaluated under an operating microscope after repair. With the leakage test device, coronal 1 mol/L glucose solution was forced toward the pulpal floor. Leakage was measured by the concentration of leaked glucose in bottom reservoir at 1, 2, 4, 7, 10, 15 and 20 days with enzymatic glucose oxidase method.
Results:
No significant difference was found between group 1 and group 2 (P > 0.05). Leakage in group 4 was obviously lower than group 3 (P < 0.05) after the 7th day.
Conclusion:
Calcium sulfate significantly improved the sealing effect of resin and provided successful barriers against its overextension.

