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Right ventricular involvement in Takotsubo cardiomyopathy
Dariusch Haghi1, Anastasios Athanasiadis, Theano Papavassiliu
1Medical Department, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, Mannheim 68167, Germany.
European Heart Journal
|September 27, 2006
Summary
Right ventricular involvement is common in Takotsubo cardiomyopathy (TTC), affecting 26% of patients. This involvement is linked to reduced left ventricular function and may be indicated by pleural effusion.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Heart Failure
Background:
- Takotsubo cardiomyopathy (TTC) is an acute heart condition.
- Right ventricular (RV) involvement in TTC is not well-characterized.
Purpose of the Study:
- To determine the incidence and clinical significance of RV involvement in Takotsubo cardiomyopathy.
Main Methods:
- Cardiovascular magnetic resonance (CMR) was performed on 34 patients with TTC.
- RV wall motion abnormalities (WMAs) and left ventricular ejection fraction (LVEF) were assessed.
- Correlation with clinical findings such as pleural effusion was analyzed.
Main Results:
- RV WMAs were observed in 26% of TTC patients.
- Patients with RV involvement had significantly lower LVEF (40% vs. 48%).
- Pleural effusion was more common (67% vs. 8%) and predictive of RV dysfunction.
Conclusions:
- Right ventricular involvement is a frequent finding in Takotsubo cardiomyopathy.
- RV dysfunction is associated with more severe left ventricular systolic impairment.
- Pleural effusion can be a clinical indicator of RV involvement in TTC.
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