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Updated: Jul 19, 2026
03:57
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
[Early PTH assay after total thyroidectomy: predictive factor for post operative hypocalcemia?].
A Bozec1, N Guevara, S Bailleux
1CHU Nice, Service d'ORL et de Chirurgie Cervico-Faciale, Nice, France. alex.bozec@freesbee.fr
Revue De Laryngologie - Otologie - Rhinologie
|September 30, 2006
Summary
Early parathyroid hormone (PTH) measurement after thyroidectomy can predict hypocalcemia. A PTH level of 16 pg/mL or less one hour post-surgery indicates a high risk of developing low calcium levels.
Area of Science:
- Endocrinology
- Surgical Complications
- Oncology
Context:
- Total thyroidectomy is frequently associated with hypocalcemia.
- Monitoring for post-operative hypocalcemia is a primary reason for prolonged hospital stays.
Purpose:
- To evaluate the utility of early parathyroid hormone (PTH) assay in predicting hypocalcemia following total thyroidectomy.
Summary:
- A prospective study involving 62 patients undergoing total thyroidectomy assessed PTH levels one hour post-surgery.
- A parathyroid hormone (PTH) level ≤16 pg/mL accurately predicted hypocalcemia (100% sensitivity, 71.7% specificity).
- Patients with PTH >16 pg/mL remained normocalcemic, demonstrating the test's high negative predictive value.
Impact:
- Early PTH measurement can identify patients at risk for hypocalcemia.
- This allows for timely calcium and vitamin D replacement therapy.
- Potentially reduces complications and shortens hospital stays.
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