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Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
[Primary sub-mandibular gland tumours: experience based on 68 cases].
A Oudidi1, M N El-Alami, M Boulaich
1Hôpital des Spécialités, Service ORL & Chirurgie Maxillo-Faciale, Rabat, Maroc. otorhino@hotmail.com
Revue De Laryngologie - Otologie - Rhinologie
|September 30, 2006
Summary
Sub-mandibular gland tumors are more frequently malignant than parotid tumors. Prompt diagnosis and appropriate management are crucial for better patient outcomes in sub-mandibular gland tumor cases.
Area of Science:
- Otorhinolaryngology
- Head and Neck Surgery
- Oncology
Context:
- Sub-mandibular gland tumors present unique clinical and therapeutic challenges compared to parotid tumors.
- This study reviews a retrospective series of sub-mandibular gland tumors treated between 1986 and 2000.
- The literature on sub-mandibular gland tumors is also reviewed.
Purpose:
- To report the clinical experience with sub-mandibular gland tumors.
- To analyze the characteristics, diagnosis, and treatment of these tumors.
- To highlight the importance of timely and accurate management.
Summary:
- A review of 68 sub-mandibular gland tumors (37 benign, 31 malignant) revealed pleomorphic adenoma as the most common benign type.
- Adenoid cystic carcinoma was the most frequent malignant sub-mandibular gland tumor, followed by epidermoid carcinoma, adenocarcinoma, mucoepidermoid carcinoma, and lymphoma.
- Malignancy signs included pain, cervical adenopathy, nerve palsy, and invasion; treatment involved surgical excision, with neck dissection, radiotherapy, or chemotherapy for malignant cases.
Impact:
- Sub-mandibular gland tumors exhibit a higher malignancy rate than parotid tumors.
- Delayed diagnosis or inadequate treatment of sub-mandibular gland tumors can lead to poor patient prognosis.
- This study underscores the need for vigilant diagnosis and tailored therapeutic strategies for sub-mandibular gland malignancies.
