Related Experiment Video
Updated: Jul 19, 2026

Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale
Published on: May 28, 2021
Update on dermal substitutes
Michael Ehrenreich1, Zbigniew Ruszczak
1Dermatology, New Jersey Medical School, 185 South Orange Avenue, Newark 07103, USA. ehrenrmi@umdnj.edu
Abstract:
Tissue-engineered biological dressings offer promise in the treatment of burns, chronic ulcers, donor site and other surgical wounds, and a variety of dermatologic conditions. Despite this promise, cellular tissue-engineered products such a Dermagraft and Apligraf have suffered setbacks in recent years with a lower market share than the commercial promoters of these products anticipated. AlloDerm acellular dermal matrix, an older technology than these cell-based products, has made strong progress in winning over clinicians in various disciplines. Similarly, Integra Bilayer Matrix Wound Dressing (BMWD) continues to gain acceptance beyond its original burn audience. A review on the products is offered.
More Related Videos
Related Concept Videos
Renewal of Skin Epidermal Stem Cells
Transdermal Drug Delivery Systems
Clinical Applications of Epidermal Stem Cells
Reticular Dermis
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Tissue Renewal without Stem Cells
However, failure of such a system...

