Related Experiment Video
Updated: Jul 19, 2026
10:21
Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin
Published on: September 12, 2019
Critical appraisal of the current practice in murine TNBS-induced colitis
Anje A te Velde1, Marleen I Verstege, Daniel W Hommes
1Centre for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. a.a.tevelde@amc.uva.nl
Inflammatory Bowel Diseases
|October 3, 2006
Abstract:
There is no standard practice in the induction of colitis by 2,4,6-trinitrobenzene sulfonic acid. In this review the current practice in 2,4,6-trinitrobenzene sulfonic acid colitis is studied using 20 recently published articles. We compare the different protocols, discuss the mechanism of disease and give recommendations for the future use of the model.
