Related Experiment Videos
The effect of medication adherence on health care utilization in bipolar disorder
Kim H Lew1, Eunice Y Chang, Krithika Rajagopalan
1Health Informatics and Outcomes Research, Prescription Solutions, Irvine, California 92614-6223, USA.
Abstract:
A retrospective analysis of electronic prescription and medical claims representing approximately 1.4 million managed care commercial health plan members with mental health benefits was conducted. The effect of patient adherence to traditional mood-stabilizer therapy (lithium, valproate, carbamazepine, lamotrigine, or oxcarbazepine) for bipolar disorder on mental health-related hospitalization was assessed among 1,399 patients (mean age, 42.9 yr; 66.3% female) studied. Reduced adherence to traditional mood-stabilizing therapy (< 80%) in patients with bipolar disorder was associated with significantly greater risk of mental health-related, emergency room visits (odds ratio, 1.98; 95% confidence interval, 1.38-2.84) and inpatient hospitalizations (odds ratio, 1.71; 95% confidence interval, 1.27-2.32), even after adjusting for age, gender, and comorbidity.
Related Concept Videos
Drug Therapy
Antianxiety Medications
Mania and Antimanic Drugs: Overview
Psychosis: Goals of Pharmacotherapy
Bipolar Disorder
Psychosis and Antipsychotic Drugs: Overview
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment