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Updated: Jul 19, 2026

Regulatory T cells: Therapeutic Potential for Treating Transplant Rejection and Type I Diabetes
Published on: August 20, 2007
Regulatory T-cells: immunomodulators in health and disease
Karen Scalzo1, Magdalena Plebanski, Vasso Apostolopoulos
1Vaccine and Infectious Disease Laboratory, Burnet Institute at Austin, Studley Rd, Heidelberg Victoria 3084, Australia.
Abstract:
Regulation of immune responses is crucial in order to maintain immunological self-tolerance. This is maintained in the periphery by a number of cell types that have the capacity to control and regulate immune responses, thus preventing reactivity to self while monitoring appropriate, non-exuberant responses to non-self-antigens. The various mechanisms of regulation will be discussed in this review together with how this knowledge could be used to develop better drugs and treatments for various diseases.
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