Related Experiment Videos
[Concentric left ventricular hypertrophy in patients with hypertension. When should ventricular hyperexcitability be
M Galinier1, P Massabuau, J Puel
1Service de cardiologie clinique et expérimentale, CHU Rangueil, Toulouse.
Insights
Concentric left ventricular hypertrophy (LVH) in essential hypertension is linked to increased ventricular ectopy. Severe LVH, indicated by septal thickness, correlates with more premature ventricular contractions (PVCs) and higher Lown
Area of Science:
- Cardiology
- Hypertension Research
- Cardiac Electrophysiology
Context:
- Essential hypertension is a common condition.
- Left ventricular hypertrophy (LVH) is a known complication.
- Ventricular ectopic activity can increase cardiovascular risk.
Purpose:
- To investigate the relationship between concentric left ventricular hypertrophy (LVH) and ventricular ectopic activity in patients with essential hypertension.
- To determine if the degree of LVH correlates with the severity of ventricular ectopy.
Summary:
- This study analyzed 56 patients with essential hypertension, comparing those with and without concentric LVH using 24-hour Holter monitoring.
- Results indicate that moderate to severe concentric LVH, identified by echocardiography (septal thickness ≥ 12 mm), is associated with increased premature ventricular contractions (PVCs) and higher Lown's grades of ventricular ectopy.
- A strong correlation (r = 0.6, p < .0001) was found between septal thickness and Lown's classification.
Impact:
- Findings highlight the clinical significance of concentric LVH in predicting ventricular arrhythmias in hypertensive patients.
- This research may inform risk stratification and management strategies for essential hypertension.
- Understanding this link can aid in early detection and intervention to prevent adverse cardiac events.
Abstract:
The main objective is to determine when concentric left ventricular hypertrophy (LVH) increased ventricular ectopic activity in essential hypertension. Twenty-four hours Holter monitoring was recorded in 56 patients with essential hypertension: 20 without LVH and 36 with concentric LVH determined by echocardiography (left ventricular mass greater than 215 g). According the degree of septal thickness (ST), patients were classed in 4 groups: (formula; see text) This study allows to conclude that mean and severe concentric LVH (ST greater than or equal to 12) detected by echo are associated with a greater PVC and a higher Lown's class ventricular ectopy. The degree of ST was strong correlated with the Lown's classification (r = 0.6, p less than .0001).