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Updated: Jul 19, 2026

Permanent Cerebral Vessel Occlusion via Double Ligature and Transection
Published on: July 21, 2013
Cerebrovascular disease
1Department of Anesthesia and Perioperative Medicine, University of Western Ontario and London Health Sciences Centre, London, Ontario, Canada. iherrick@uwo.ca
Insights
Carotid endarterectomy is a key stroke prevention surgery. Recent findings guide patient selection and perioperative care, especially for older patients with comorbidities, to reduce risks.
Area of Science:
- Neurology
- Vascular Surgery
- Anesthesiology
Background:
- Carotid endarterectomy (CEA) is a primary surgical treatment for stroke prevention in patients with extracranial cerebrovascular disease.
- Multicenter trial subgroup analyses have significantly enhanced understanding of patient selection and perioperative risks associated with CEA.
Purpose of the Study:
- To review recent advancements in the understanding of appropriate carotid endarterectomy use.
- To outline recent developments and strategies impacting perioperative care for CEA patients.
Main Methods:
- Literature review of multicenter trials and recent studies.
- Analysis of findings related to patient selection and perioperative management.
Main Results:
- Recent advances refine the appropriate indications for carotid endarterectomy.
- New strategies are emerging for optimizing perioperative care and reducing complications.
Conclusions:
- Anesthesiologists will increasingly manage older, higher-risk patients undergoing CEA.
- Effective management of comorbidities, particularly hypertension and cardiac risks, is crucial for reducing perioperative morbidity and mortality.
Purpose Of Review:
Carotid endarterectomy remains the preferred surgical intervention for the prevention of stroke among patients with extracranial cerebrovascular disease. Subgroup analyses of the results of several multicentre trials have contributed substantially to our understanding of the appropriate selection of patients and the perioperative risk associated with this procedure.
Recent Findings:
This review describes recent advances in our understanding of the appropriate use of carotid endarterectomy, and outlines recent developments and strategies that are likely to influence the perioperative care of these patients.
Summary:
As current clinical guidelines for the use of carotid endarterectomy unfold, anaesthesiologists can expect to care more frequently for older patients and those at increased risk of complications. The perioperative management of co-existing diseases, particularly the control of hypertension and the strategies aimed at reducing the risk of cardiac complications, will contribute substantially to reducing perioperative morbidity and mortality.
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