[Estimation and prediction of functional changes in organisms in space flight]

Area of Science:

• Physiology
• Space Medicine
• Biomedical Engineering

Context:

• Understanding organism health requires evaluating transitional states between health and illness, termed prenosological states.
• Health is intrinsically linked to an organism's adaptive capacity, regulatory system tension, and functional reserves.
• Heart rate variability analysis serves as a key method for assessing regulatory system tension.

Purpose:

• To explore theoretical and applied challenges in estimating the functional state and health level of an organism.
• To investigate the physiological adaptations and regulatory system responses during prolonged weightlessness in spaceflight.
• To develop a mathematical model for characterizing functional states and classifying vegetative regulation patterns.

Summary:

• This research examines organism functional states and health, focusing on prenosological conditions and the role of regulatory systems.
• Heart rate variability analysis is employed to quantify regulatory system tension, providing insights into health status.
• The study presents findings from spaceflight, detailing functional state changes during adaptation to weightlessness and introducing a mathematical model.

Impact:

• Identifies four distinct types of vegetative regulation based on adaptive reactions observed during spaceflight.
• Provides valuable data on the physiological impact of long-duration space missions on International Space Station crew members.
• Contributes to a deeper understanding of human physiological adaptation and health monitoring in extreme environments.