Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Type IV Collagen of Basal Lamina

Type IV Collagen of Basal Lamina

Type IV collagen is a 400 nm long, network-forming collagen that acts as a barrier between the epithelial and endothelial cells. Type IV collagen forms the backbone of the basement membrane by scaffolding with laminin, entactin, proteoglycans, and fibronectin. Apart from rendering structural support to the basement membrane, it also helps entail signaling potentials necessary for both pathological and physiological functions.
A type IV collagen molecule has six alpha chains which can exist in...

Fibril-associated Collagen

Fibril-associated Collagen

Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...

Healing II: Complications

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Inefficient Magnetic-Field Amplification in Supersonic Laser-Plasma Turbulence.

Physical review letters·2021

Same author

Characterization of innate and adaptive immune cells involved in the foreign body reaction to polypropylene meshes in the human abdomen.

Hernia : the journal of hernias and abdominal wall surgery·2021

Same author

Tissue remodeling macrophages morphologically dominate at the interface of polypropylene surgical meshes in the human abdomen.

Hernia : the journal of hernias and abdominal wall surgery·2020

Same author

META Score: An International Consensus Scoring System on Mesh-Tissue Adhesions.

World journal of surgery·2020

Same author

Comment to: analysing topics using different methods promotes constructive debates. Author's reply.

Hernia : the journal of hernias and abdominal wall surgery·2020

Same author

[Oligometastasized colorectal cancer-modern treatment strategies].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2018

Search research articles

Related Experiment Video

Updated: Jul 19, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

Laparoscopy and collagen metabolism.

R Rosch¹, K Junge, M Binnebösel

¹Department of Surgery of the RWTH-Aachen, University Hospital Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany. r.rosch@chir.rwth-aachen.de

Hernia : the Journal of Hernias and Abdominal Wall Surgery

|October 7, 2006

Summary

Collagens are crucial for wound healing and scar formation. This review examines how endoscopic surgery impacts collagen biology, a key area for surgical innovation.

More Related Videos

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

Published on: November 11, 2020

Preparing Porcine Eyes for Confocal Reflectance Microscopy to Visualize the Vitreous Collagen Fiber Network

Preparing Porcine Eyes for Confocal Reflectance Microscopy to Visualize the Vitreous Collagen Fiber Network

Published on: October 17, 2025

Related Experiment Videos

Last Updated: Jul 19, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

Quantifying Fibrillar Collagen Organization with Curvelet Transform-Based Tools

Published on: November 11, 2020

Preparing Porcine Eyes for Confocal Reflectance Microscopy to Visualize the Vitreous Collagen Fiber Network

Preparing Porcine Eyes for Confocal Reflectance Microscopy to Visualize the Vitreous Collagen Fiber Network

Published on: October 17, 2025

Area of Science:

Biochemistry
Surgical Innovation
Wound Healing Research

Background:

Collagens are essential structural proteins in tissue repair and scar development.
Understanding collagen metabolism is critical for evaluating surgical techniques.
Endoscopic surgery is increasingly common for abdominal conditions.

Purpose of the Study:

To review the existing literature on the impact of endoscopic surgical techniques on collagen biology.
To assess how minimally invasive approaches influence collagen metabolism during wound healing and scar formation.

Main Methods:

Comprehensive literature search of studies investigating endoscopic surgery and collagen.
Analysis of research focusing on collagen synthesis, degradation, and organization post-endoscopic procedures.

Main Results:

Endoscopic techniques may alter collagen deposition and remodeling patterns compared to open surgery.
Specific findings on collagen types, cross-linking, and tensile strength in endoscopic procedures require further investigation.

Conclusions:

Endoscopic surgery's influence on collagen metabolism warrants continued research.
Further studies are needed to fully elucidate the long-term effects on scar quality and tissue integrity.