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Updated: Jul 19, 2026

A Tandem Liquid Chromatography–Mass Spectrometry-based Approach for Metabolite Analysis of Staphylococcus aureus
Published on: March 28, 2017
[Regulatory functions of bacterial exometabolites]
Abstract:
This review deals with the issue of growth autoregulation and survival in bacterial cultures under starvation conditions. Based on our results and on published data, the conclusion has been drawn that low-molecular products of metabolism (carboxylic acids, amino acids, and other metabolites) perform regulatory functions. The same compounds also control the ecological relationship between microorganisms at the interspecific level, and affect their antagonistic activity. It is suggested that complexes of bacterial metabolites can be used for controlling the composition of various microbiocenosis, including those of humans.
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