Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Morphogenesis02:19

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
Canonical Wnt Signaling Pathway02:54

Canonical Wnt Signaling Pathway

The gene encoding the main signaling molecules of the Wnt signaling pathways (the Wnt proteins) was discovered almost four decades ago by Nüsslein-Volhard and Wieschaus. They identified and originally named the gene "wingless" (wg) after a phenotype discovered during their landmark genetic screen in Drosophila for body pattern defects. At around the same time, another researcher named Harold Varmus found that a murine tumor virus activates the mammalian wg homolog, Int-1, which results in tumor...
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal01:22

Role of Ephrin-Eph Signalling in Intestinal Stem Cell Renewal

Erythropoietin-producing hepatocellular carcinoma receptor (Eph) and its ligand, Eph receptor-interacting protein (Ephrin) were first discovered in the human carcinoma cell line, hence the name. Ephrin-Eph interaction guides cells to reach their appropriate location in adult tissues. They also play an essential role in the immune system by helping in immune cell migration, adhesion, and activation. Based on their structure and function, Eph is divided into two classes — EphA and EphB.
Cellular Differentiation00:57

Cellular Differentiation

How does a complex organism such as a human develop from a single cell? It all starts from a single fertilized egg which gives rise to a vast array of cell types, such as nerve cells, muscle cells, and epithelial cells that characterize the adult? Throughout development and adulthood, cellular differentiation leads cells to assume their final morphology and physiology. Differentiation is the process by which unspecialized cells become specialized to carry out distinct functions.
A zygote is a...
Role Of Notch Signalling In Intestinal Stem Cell Renewal01:12

Role Of Notch Signalling In Intestinal Stem Cell Renewal

Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic insights into the improvement of Chinese fir from ancient domestication continuum to modern breeding.

Nature communications·2026
Same author

Unlocking yield potential of wheat via inflorescence design.

Science bulletin·2025
Same author

Functional conservation and divergence of the WOX gene family in regulating meristem activity: From Arabidopsis to crops.

Plant physiology·2025
Same author

Competence for transcellular infection in the root cortex involves a post-replicative, cell-cycle exit decision in <i>Medicago truncatula</i>.

eLife·2025
Same author

LEC2 induces somatic cell reprogramming through epigenetic activation of plant cell totipotency regulators.

Nature communications·2025
Same author

Integration of basal and apical embryo lineage regulators controls F-actin cable integrity and zygote asymmetry in <i>Arabidopsis</i>.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same journal

Coming full circle: Neural crest marker FOXD3 regulates SHH expression in the floorplate and neural tube morphogenesis.

Developmental biology·2026
Same journal

The oocytes of basal dermapterans lack the posterior pole lysosomal compartment (PPLC).

Developmental biology·2026
Same journal

A central role for Islr2 (Linx) in direct pathway striatal projection neurons for the correct formation of the internal capsule and cerebral peduncle.

Developmental biology·2026
Same journal

Shared candidate genes associated with variation in egg size in cold-adapted and artificially selected Drosophila melanogaster.

Developmental biology·2026
Same journal

The molecular mechanism underlying melatonin-mediated repair of ovarian damage in mice exposed to abnormal light cycles.

Developmental biology·2026
Same journal

The Drosophila ovarian terminal filament imports lipophilic molecules that support cyst and follicle development within the ovariole.

Developmental biology·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

Studying Wnt Signaling During Patterning of Conducting Airways
13:00

Studying Wnt Signaling During Patterning of Conducting Airways

Published on: October 16, 2016

WUSCHEL regulates cell differentiation during anther development.

Florian Deyhle1, Ananda Kumar Sarkar, Elise J Tucker

  • 1Institute of Biology III, University of Freiburg, Schänzlestrasse 1, 79104 Freiburg, Germany.

Developmental Biology
|October 10, 2006
PubMed
Summary
This summary is machine-generated.

The homeobox gene WUSCHEL is crucial for male organogenesis, regulating cell differentiation in anthers. WUSCHEL mutations prevent pollen release by disrupting stomium and septum cell development.

More Related Videos

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
07:34

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Published on: February 16, 2017

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
06:49

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay

Published on: January 12, 2022

Related Experiment Videos

Last Updated: Jun 24, 2026

Studying Wnt Signaling During Patterning of Conducting Airways
13:00

Studying Wnt Signaling During Patterning of Conducting Airways

Published on: October 16, 2016

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
07:34

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Published on: February 16, 2017

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay
06:49

Analysis of Cell Differentiation, Morphogenesis, and Patterning During Chicken Embryogenesis Using the Soaked-Bead Assay

Published on: January 12, 2022

Area of Science:

  • Plant biology
  • Developmental biology
  • Genetics

Background:

  • Anther development involves intricate cell specification for male gametophyte formation.
  • The homeobox gene WUSCHEL (WUS) is known for regulating stem cell maintenance.

Purpose of the Study:

  • To investigate the role of WUSCHEL in cell type specification during male organogenesis.
  • To understand the molecular mechanisms underlying anther development and pollen release.

Main Methods:

  • Analysis of WUS expression patterns during anther development.
  • Characterization of wus mutants to observe developmental defects.

Main Results:

  • WUS expression is initiated early in anther development in stomium precursor cells.
  • In wus mutants, stomium and septum cells fail to differentiate and undergo programmed cell death.
  • This failure leads to an intact anther that cannot release pollen.

Conclusions:

  • WUSCHEL plays a critical role in specifying cell types and regulating cell fate during male organogenesis.
  • A novel WUS-regulated pathway, distinct from CLAVATA3 activation, operates in anthers.
  • WUS-expressing cells act as a conserved signaling module controlling undifferentiated cell behavior.