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Updated: Jul 19, 2026

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Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
Published on: August 19, 2012
The chemical modification of liposome surfaces via a copper-mediated [3 + 2] azide-alkyne cycloaddition monitored by
Silvia Cavalli1, Alicia R Tipton, Mark Overhand
1Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Abstract:
A generic method for the efficient in-situ modification of liposomes is described based on "click" chemistry, and a simple colorimetric assay is developed for monitoring the reaction.

