Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autoimmune hepatitis.

D Vergani1, G Mieli-Vergani

  • 1Institute of Hepatology, University College London, 69-75 Chenies Mews, London WC1E 6HX, United Kingdom.

Current Opinion in Gastroenterology
|October 13, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-world management of juvenile autoimmune liver disease.

United European gastroenterology journal·2018
Same author

Interferon-free therapy in hepatitis C virus mixed cryoglobulinaemia: a prospective, controlled, clinical and quality of life analysis.

Alimentary pharmacology & therapeutics·2018
Same author

Spectroscopic identification of r-process nucleosynthesis in a double neutron-star merger.

Nature·2017
Same author

Immunosuppressive drugs affect interferon (IFN)-γ and programmed cell death 1 (PD-1) kinetics in patients with newly diagnosed autoimmune hepatitis.

Clinical and experimental immunology·2017
Same author

Autoimmune hepatitis: From mechanisms to therapy.

Revista clinica espanola·2016
Same author

HBsAg plasma level kinetics: a new role for an old marker as a therapy response predictor in vertically infected children on combination therapy.

Journal of viral hepatitis·2014
Same journal

Endoscopic techniques to minimize gastroesophageal reflux during peroral endoscopic myotomy.

Current opinion in gastroenterology·2026
Same journal

Postendoscopy esophageal adenocarcinoma and neoplasia: current status and future directions.

Current opinion in gastroenterology·2026
Same journal

The complement system in inflammatory bowel disease: from early observations to emerging frontiers.

Current opinion in gastroenterology·2026
Same journal

Goblet cell-associated antigen passages in health and disease.

Current opinion in gastroenterology·2026
Same journal

Inflammatory bowel diseases 2026: form, function and therapeutic considerations for the epithelial barrier.

Current opinion in gastroenterology·2026
Same journal

Dietary protein as a regulator of colitis and colorectal cancer.

Current opinion in gastroenterology·2026
See all related articles

Autoimmune hepatitis (AIH) is an immune-mediated liver condition primarily affecting women. Early diagnosis and immunosuppressive treatment are crucial for managing AIH and related overlap syndromes.

Area of Science:

  • Hepatology
  • Immunology
  • Internal Medicine

Background:

  • Autoimmune liver disease comprises various disorders, including autoimmune hepatitis (AIH).
  • AIH is characterized by immune cell infiltration of the liver, specific autoantibodies, and elevated immunoglobulin G (IgG).
  • It predominantly affects women and can present acutely or insidiously.

Purpose of the Study:

  • To review current knowledge on autoimmune hepatitis (AIH).
  • Focus on pathogenesis, differential diagnosis, treatment strategies, and clinical course.
  • Highlight overlap syndromes associated with AIH.

Main Methods:

  • Review of relevant scientific literature.
  • Analysis of diagnostic criteria and treatment responses.

Related Experiment Videos

  • Synthesis of information on disease presentation and progression.

    • Main Results:

    • AIH diagnosis no longer requires a 6-month symptom duration; prompt treatment is recommended.
    • Immunosuppressive therapy is effective for AIH.
    • Understanding of AIH pathogenesis, diagnosis, and management has advanced.

    Conclusions:

    • Autoimmune hepatitis requires timely diagnosis and immunosuppressive treatment.
    • Overlap syndromes necessitate careful consideration in AIH management.
    • Continued research is vital for improving patient outcomes in autoimmune liver diseases.