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Updated: Jul 19, 2026

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering

Published on: June 1, 2016

Nanostructured thermosensitive polymers with radical scavenging ability.

Guangchang Zhou¹, Issifu I Harruna, Weilie L Zhou

¹Department of Chemistry, Clark Atlanta University, 223 James P. Brawley DR SW, Atlanta, GA 30314, USA.

Chemistry (Weinheim an Der Bergstrasse, Germany)

|October 13, 2006

Summary

Researchers synthesized a novel thermosensitive polymer by combining fullerenes with poly(N-isopropylacrylamide). This new material retains its temperature-responsive properties and shows promise as a radical scavenger.

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Area of Science:

Polymer Chemistry
Materials Science
Nanotechnology

Background:

Poly(N-isopropylacrylamide) is a well-known thermosensitive polymer.
Fullerenes (C60) are carbon nanomaterials with unique electronic and antioxidant properties.
Combining polymers with fullerenes can lead to novel materials with enhanced functionalities.

Purpose of the Study:

To synthesize a novel thermosensitive polymer end-capped with [60]fullerene.
To characterize the structure and properties of the synthesized fullerenated polymer.
To evaluate the thermosensitivity, solubility, self-assembly, and radical scavenging ability of the new material.

Main Methods:

Synthesis of dithiobenzoate-terminated poly(N-isopropylacrylamide) via reversible addition-fragmentation chain-transfer (RAFT) polymerization.
End-capping of the polymer with [60]fullerene (C60).
Structural characterization using FTIR, UV/Vis, NMR spectroscopy, and size exclusion chromatography (SEC).
Assessment of thermosensitivity, solubility, nanoparticle formation in methanol, and radical scavenging activity.

Main Results:

Successful synthesis of [60]fullerene end-capped poly(N-isopropylacrylamide).
The synthesized polymer retained the thermosensitive behavior of poly(N-isopropylacrylamide).
The material demonstrated good solubility in water and common organic solvents.
Formation of nanoparticle clusters in methanol was observed.
Significant radical scavenging ability was confirmed in cell viability and metabolic activity tests.

Conclusions:

A novel thermosensitive fullerenated polymer was successfully synthesized and characterized.
The new polymer exhibits retained thermosensitivity, good solubility, and self-assembly into nanoparticles.
The material shows significant potential as a radical scavenger for biomedical applications.