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Proton-proton Overhauser NMR spectroscopy with polypeptide chains in large structures.

Reto Horst1, Gerhard Wider, Jocelyne Fiaux

  • 1Institut für Molekularbiologie und Biophysik, Eidgenössische Technische Hochschule Zürich, CH-8093 Zürich, Switzerland.

Proceedings of the National Academy of Sciences of the United States of America
|October 13, 2006
PubMed
Summary

Nuclear Overhauser Effect (NOE) NMR experiments can determine the structure of large protein complexes. Optimal mixing times allow accurate measurements regardless of size or motion.

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