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Predictors of long-term survival with pulmonary metastasectomy for osteosarcomas and soft tissue sarcomas
1Division of Thoracic Diseases, Chiba Cancer Center, Chiba, Japan. smakoto@faculty.chiba-u.jp
Aim:
The control of pulmonary metastases is important for long-term survival of the patients with osteosarcomas and soft tissue sarcomas.
Methods:
To evaluate the efficacy of aggressive pulmonary metastasectomy for those patients, we reviewed 105 cases (44 osteosarcomas, and 61 soft tissue sarcomas) treated in our hospital.
Results:
The number of metastases was only the significant risk factor for the curability of the metastasectomy (logistic regression analysis, P=0.0274). The 5-year and 10-year survival rate were 43.6% and 32%. The curability was only independent prognostic factor on multivariate analysis (P=0.0008).
Conclusions:
Early detection of pulmonary metastasis, multimodal perioperative treatment, and design for minimizing the volume of resected lung tissues will enable complete and repeat resections for the achievement of long-term survival.
