Related Experiment Video
Updated: Jul 19, 2026

Use of Galleria mellonella as a Model Organism to Study Legionella pneumophila Infection
Published on: November 22, 2013
Update of Legionella infections
1Ohio State University Medical Center, Division of Infectious Diseases, Department of Internal Medicine, Columbus, OH 43210, USA. plouffe.1@osu.edu
Abstract:
Legionella spp. are significant causes of both community-acquired pneumonia and nosocomial pneumonia. More than 40 species of Legionella have now been identified. The spectrum of disease ranges from asymptomatic infection to serious disease, with two specific syndromes identified: Legionnaire's disease and Pontiac fever. Hospital-acquired infection arises from the presence of Legionella in the hospital water supply. The optimal approach for the detection and prevention of nosocomial infection is debatable-whether or not periodic sampling of hospital water systems should be carried out in the absence of clinical cases is controversial. Newer macrolides or newer fluoroquinolone agents are the preferred therapy for serious diseases caused by Legionella.
Related Concept Videos
Atypical Pneumonia
Acute Pyelonephritis II: Diagnostic Studies and Management
Inhibitors of Bacterial DNA Synthesis
Cholera
Investigation of Disease Outbreaks
Reservoir of Infection
