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Burkitt's lymphoma presenting with blindness: a case report.
M Ibrahim1, W N Ogala, F A Babaoye
1Department of Paediatrics, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Annals of Tropical Paediatrics
|January 1, 1990
Summary
A child with Burkitt's lymphoma experienced sudden vision loss due to ophthalmoplegia. Chemotherapy resolved tumors but not the blindness, highlighting a critical neuro-ophthalmic complication.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Neurology
Background:
- Burkitt's lymphoma is an aggressive non-Hodgkin lymphoma.
- Ocular involvement in Burkitt's lymphoma can occur but is less common.
Observation:
- A 10-year-old boy presented with sudden vision loss, headache, ptosis, and ophthalmoplegia.
- Jaw and abdominal tumors appeared, later confirmed as Burkitt's lymphoma via biopsy.
Findings:
- Combination chemotherapy (cyclophosphamide, vincristine, methotrexate) rapidly resolved the tumors.
- The patient's vision loss was irreversible despite tumor treatment.
Implications:
- This case underscores the potential for severe neuro-ophthalmic complications in pediatric Burkitt's lymphoma.
- Early recognition and management of ocular symptoms are crucial, though visual recovery may be limited.