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Related Experiment Video

Updated: Jul 19, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

Published on: November 2, 2013

Clinical implications of prostate-specific antigen (PSA).

¹Department of Urology, Royal Hallamshire Hospital, Sheffield S11 7JZ, UK.

Current Opinion in Urology

|October 14, 2006

Summary

Prostate-specific antigen (PSA) is a key marker for prostate cancer detection, staging, and treatment response prediction. Recent studies refine its clinical use with PSA indices like density and velocity.

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Last Updated: Jul 19, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

Area of Science:

Urology
Oncology
Biomarkers

Background:

Prostate-specific antigen (PSA) is the primary tumor marker for prostate cancer.
This review focuses on PSA's application in cancer detection, staging, and predicting treatment response.

Discussion:

Examines PSA levels in normal and 'grey' zones (2.5-10 ng/ml) for improved cancer detection.
Discusses the role of PSA indices, including PSA density, velocity, and age-specific ranges.
Analyzes recent studies on the clinical utility and standing of PSA and its indices.

Key Insights:

PSA indices significantly refine the interpretation of PSA values, enhancing diagnostic accuracy.
PSA's application extends beyond detection to disease staging and treatment outcome prediction.
Understanding PSA dynamics is crucial for effective prostate cancer management.

Outlook:

Further research is needed to fully integrate PSA indices into routine clinical practice.
Continued refinement of PSA-based strategies will improve patient stratification and treatment selection.
The evolving role of PSA highlights the importance of personalized medicine in prostate cancer care.