Related Experiment Video
Updated: Jul 19, 2026

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice
Published on: July 15, 2025
Preliminary testing for normality: some statistical aspects of a common concept
V Schoder1, A Himmelmann, K P Wilhelm
1proDERM, Institute for Applied Dermatological Research, Schenefeld, Hamburg, Germany. vschoder@proderm.de
Background:
Statistical methodology has become an increasingly important topic in dermatological research. Adequacy of the statistical procedure depends among others on distributional assumptions. In dermatological articles, the choice between parametric and nonparametric methods is often based on preliminary goodness-of-fit tests.
Aim:
For the special case of the assumption of normally distributed data, the Kolmogorov-Smirnov test is the most popular choice. We investigated the performance of this test on four types of non-normal data, representing the majority of real data in dermatological research.
Methods:
Simulations were run to assess the performance of the Kolmogorov-Smirnov test, depending on sample size and severity of violations of normality.
Results:
The Kolmogorov-Smirnov test performs badly on data with single outliers, 10% outliers and skewed data at sample sizes < 100, whereas normality is rejected to an acceptable degree for Likert-type data.
Conclusion:
Preliminary testing for normality is not recommended for small-to-moderate sample sizes.
Related Concept Videos
The Anderson-Darling Test
Introduction to Normal Distributions
Test for Homogeneity
Statistical Methods to Analyze Parametric Data: Student t-Test and Goodness-of-Fit Test
The Student's t-test is a statistical test that examines if there is a statistically significant difference between the means of two groups. This test is instrumental when dealing with data...
Testing a Claim about Mean: Known Population SD
Estimating a population mean requires the samples to be distributed normally. The data should be collected from the randomly selected samples having no sampling bias. The sample size needed to be higher than 30, and most importantly, the population standard deviation should be already known.
In most realistic situations, the population standard deviation is often unknown, but in rare circumstances, when it...
Testing a Claim about Standard Deviation
The hypothesis testing for the claim of population standard deviation (or variance) requires the data and samples to be random and unbiased. The population distribution also must be normal. There is no specific requirement on the sample size as the estimation is based on the chi-square distribution.
As a first step, the hypothesis (null and alternative) concerning the claim about...

