Sindbis virus inhibits phosphatidylcholine biosynthesis in BHK-21 cells

Sindbis virus inhibits the incorporation of [methyl-3H]choline into the phospholipids of BHK-21 cells and also inhibits the activity of the enzyme that catalyzes the final reaction involved in phosphatidylcholine biosynthesis (cytidine diphosphate-choline:1,2-diacylglycerol cholinephosphotranferase; EC 2.7.8.2).