Oriented loading of FtsK on KOPS
Related Experiment Video
Updated: Jul 19, 2026

Cargo Loading onto Kinesin Powered Molecular Shuttles
Published on: November 3, 2010
Sarah Bigot1, Omar A Saleh, François Cornet
1Laboratoire de Microbiologie et de Génétique Moléculaire, CNRS UMR5100, Toulouse, France.
Abstract:
In Escherichia coli, the ATP-dependent DNA translocase FtsK transports DNA across the site of cell division and activates recombination by the XerCD recombinases at a specific site on the chromosome, dif, to ensure the last stages of chromosome segregation. DNA transport by FtsK is oriented by 8-base-pair asymmetric sequences ('KOPS'). Here we provide evidence that KOPS promote FtsK loading on DNA and that translocation is oriented at this step.
More Related Videos
05:26PyOKR: A Semi-Automated Method for Quantifying Optokinetic Reflex Tracking Ability
Published on: April 12, 2024
11:27Studying Soft-matter and Biological Systems over a Wide Length-scale from Nanometer and Micrometer Sizes at the Small-angle Neutron Diffractometer KWS-2
Published on: December 8, 2016
Related Concept Videos
Beams with Symmetric Loadings
The M/EI...
Beams with Unsymmetric Loadings
The first moment-area theorem determines the slope at any point on the beam. This theorem indicates that the change in slope between two points on a beam...
Load along a Single Axis
Consider a beam of length L subjected to a varying load, which is a combination of parabolic and trapezoidal load distribution along the x-axis. In this case, it is essential to determine the resultant loads, their locations, and...
Stability of structures
Eccentric Loading
Impact Loading on a Cantilever Beam
When an object is dropped onto the free end of a cantilever, its potential energy due to gravity is...