Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Malign and refractory hypertension].

Georg Schaller1, Michael Wolzt

  • 1Universitätsklinik für Klinische Pharmakologie, Medizinische Universität Wien, Wien, Austria.

Wiener Medizinische Wochenschrift (1946)
|October 17, 2006
PubMed
Summary

This article discusses therapy-resistant hypertension, exploring its causes, clinical symptoms, and historical context. It highlights organ damage as a key indicator of severe arterial hypertension and examines potential therapeutic strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Donor bone marrow together with recipient regulatory T cells induces chimerism without irradiation in kidney transplantation.

Science translational medicine·2026
Same author

Investigating the risk of obesity in European night shift workers: a study protocol for cross-sectional and mechanistic studies in the SHIFT2HEALTH Project.

Obesity facts·2026
Same author

Effect of a Single Oral Dose of Dexamphetamine or Zolpidem on Attention and Reaction Time in Healthy Men.

Fundamental & clinical pharmacology·2026
Same author

Biophysical and Raman Spectroscopy assessment of drug-induced photosensitivity: Insights from a randomised controlled pilot study.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2026
Same author

Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Changes the Composition of the Oral, But Not the Intestinal Microbiome.

Molecular nutrition & food research·2025
Same author

Dapagliflozin prevents vascular ischemia-reperfusion injury in healthy young males: a randomized, placebo-controlled, double-blinded trial.

Scientific reports·2025

Area of Science:

  • Cardiology
  • Nephrology
  • Neurology

Context:

  • Arterial hypertension can lead to severe organ damage, particularly affecting the cardiovascular system, central nervous system, kidneys, and retina.
  • Hypertensive emergencies signify a rapid decline in organ function, while therapy-resistant hypertension presents a slower, more insidious progression.

Purpose:

  • To review historical trends in terminology and epidemiology of arterial hypertension.
  • To elucidate the clinical manifestations and underlying causes of therapy-resistant hypertension.
  • To explore potential therapeutic strategies for managing resistant hypertension.

Summary:

  • Early organ damage in arterial hypertension indicates a poor prognosis, with hypertensive emergencies causing acute deterioration and resistant forms showing slower progression.
  • This review examines the historical evolution of hypertension terminology and epidemiology, alongside clinical symptoms and etiological factors contributing to therapy-resistant hypertension.
  • Focus is placed on secondary hypertension causes and resistance mechanisms in primary hypertension, with an overview of therapeutic interventions.

Impact:

  • Provides a comprehensive overview of therapy-resistant hypertension, aiding clinicians in diagnosis and management.
  • Contributes to understanding the long-term consequences of uncontrolled high blood pressure on vital organs.
  • Informs future research directions for novel therapeutic approaches to refractory hypertension.

Related Experiment Videos