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Updated: Jul 19, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
Published on: September 16, 2017
An exploration of patients' experiences of anti-TNF therapy
1Ashfield Health Care Ltd, Ashby de la Zouch, Leicestershire. jedwards@ashfieldhealthcare.com
Objective:
To explore the experience of rheumatoid arthritis patients receiving anti-tumour necrosis factor (anti-TNF) therapy on physical, psychological and social well-being.
Method:
Seven patients with rheumatoid arthritis (RA) who received six months of infliximab were interviewed in depth by one researcher to identify their experiences of this treatment. The interviews were tape-recorded and analysed using Colaizzi's procedural steps.
Results:
Four main categories were identified from the interview relating to the patient's experience of anti-TNF therapy. These included: The impact of living with RA on physical, psychological and social function. The influence of anti-TNF therapy on physical, psychological and social function. The experience of attending for treatment. The impact of discontinuing anti-TNF treatment.
Conclusion:
All seven patients experienced benefits from receiving anti-TNF therapy. These benefits were not maintained once the treatment period was completed.
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