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Published on: February 9, 2021

Urinary calcium excretion in healthy Turkish children

F Sönmez1, B Akçanal, Ayça Altincik

  • 1Division of Pediatric Nephrology, Faculty of Medicine, Adnan Menderes University, Aydin, Türkiye. ferahsonmez@yahoo.com

International Urology and Nephrology
|October 18, 2006
PubMed

Insights

This study established age-related urinary calcium excretion percentiles for healthy Turkish children, finding hypercalciuria in 9.6% and identifying regional variations. Age and weight showed poor negative correlations with calcium levels.

Area of Science:

  • Pediatric Nephrology
  • Clinical Biochemistry
  • Public Health

Background:

  • Urinary calcium excretion is a key indicator of kidney health in children.
  • Establishing age-specific reference ranges is crucial for diagnosing hypercalciuria.
  • Regional variations may influence urinary calcium levels.

Purpose of the Study:

  • To determine age-related percentile values for urinary calcium excretion in healthy Turkish children.
  • To ascertain the prevalence of hypercalciuria within this population.
  • To identify factors influencing urinary calcium excretion.

Main Methods:

  • A cross-sectional study involving 2252 healthy Turkish children aged 15 days to 15 years.
  • Urinary calcium/creatinine concentration ratio measured in non-fasting urine samples.
  • Statistical analysis to determine percentile values and influencing factors.

Main Results:

  • The mean urinary calcium/creatinine ratio was 0.092 ± 0.123.
  • Hypercalciuria prevalence was 9.6% (ratio > 0.21).
  • Significant differences in urinary calcium/creatinine ratios were observed based on district, altitude, and ethnic origin. Age and weight showed weak negative correlations.

Conclusions:

  • Age-specific reference values for urinary calcium/creatinine ratios are essential for pediatric populations.
  • Regional and demographic factors can impact urinary calcium excretion.
  • Further research is needed to establish country-specific and region-specific reference ranges.

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