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Updated: Jul 19, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
Published on: June 8, 2022
Successful double bioprosthetic valve replacement in a 64-year-old man with carcinoid syndrome and bipolar disorder:
Sarah S Tang1, Michael Y Henein, Anthony De Souza
1Department of Cardiac Surgery, Royal Brompton Hospital, London, UK. stang@doctors.org.uk
Abstract:
The case is described of a 64-year-old man with bipolar disorder and severe carcinoid heart disease who required a double valve replacement. Multidisciplinary team involvement and extensive preoperative investigations resulted in a successful regimen which prevented reactivation of carcinoid syndrome and avoided the serious side effects of lantreotide and lithium therapy. In addition, two bioprosthetic valves were used, thereby avoiding the potential complications of anticoagulation in a patient with known hepatic metastases.
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