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Related Experiment Videos

A new efficient NanoTip lead.

K Stokes1, T Bird

  • 1Medtronic, Inc., Minneapolis, MN 55430.

Pacing and Clinical Electrophysiology : PACE
|December 1, 1990
PubMed
Summary
This summary is machine-generated.

This study introduces a novel 1.5 mm2 porous, platinized, steroid-eluting electrode for cardiac pacing leads. The new electrode demonstrates excellent performance with low thresholds and high pacing impedance in canine models.

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Implantable Electronics

Background:

  • Ideal cardiac pacing leads require low, stable thresholds, high pacing impedance, and reliable sensing.
  • Existing leads with low thresholds often exhibit pacing impedance around 600 omega.
  • Decreasing electrode surface area can increase pacing impedance, but raises concerns about performance.

Purpose of the Study:

  • To develop and evaluate a novel, small-surface-area electrode for cardiac pacing leads.
  • To assess the pacing threshold, impedance, and sensing capabilities of the new electrode design.

Main Methods:

  • Development of a 1.5 mm2 porous, platinized, steroid-eluting electrode.
  • Evaluation of the electrode's performance in canine studies.

Related Experiment Videos

  • Measurement of chronic thresholds, pacing impedance, and R and P wave source impedance.

    • Main Results:

    • Achieved low chronic thresholds: approximately 0.65 V (ventricular) and 0.42 V (atrial) at 0.5 msec.
    • Demonstrated high chronic pacing impedance in the 1200-1300 omega range.
    • Observed excellent sensing with doubled P wave amplitudes compared to typical canine measurements.

    Conclusions:

    • The novel 1.5 mm2 electrode exhibits excellent performance characteristics for cardiac pacing.
    • This design overcomes previous limitations of small electrodes, offering high impedance and effective sensing.
    • The steroid-eluting feature may contribute to stable, low chronic thresholds.