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Fraser syndrome in a 96-year-old female
Mario Impallomeni1, Deepak Subramanian, Nazim Mahmood
1Imperial College London, London, UK.
Age and Ageing
|October 19, 2006
Abstract:
Fraser syndrome is an autosomal recessive disorder in which the life expectancy is <1 year. The main features are cryptophthalmos, ear, nose and skeletal malformations, syndactyly, laryngeal stenosis and malformation of the uro-genital system, lungs, liver and central nervous system (CNS). We report the clinical, laboratory and post-mortem findings of this condition in an elderly woman aged 96 years. She is the oldest known patient with Fraser syndrome.
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