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Published on: October 12, 2017
[Examination of urine in the child]
1Pädiatrische Nephrologie, Universitäts-Kinderklinik Bern, Inselspital, Bern. giacomo.simonetti@insel.ch
Insights
Obtaining clean urine samples from infants and toddlers can be challenging. This guide details effective pediatric urine collection methods and interpretation of results for accurate diagnosis.
Area of Science:
- Pediatric Nephrology
- Clinical Chemistry
- Microbiology
Context:
- Urine specimen collection in children, especially infants and toddlers, presents unique challenges.
- Accurate urinalysis is crucial for diagnosing various pediatric conditions, including urinary tract infections and kidney diseases.
- Established methods for urine collection and interpretation are essential for reliable diagnostic outcomes.
Purpose:
- To provide a comprehensive overview of pediatric urine specimen collection techniques.
- To clarify the diagnostic utility of different urine collection methods.
- To guide the interpretation of urinalysis findings in pediatric patients.
Summary:
- Clean catch, transurethral catheterization, and suprapubic aspiration are discussed for urine collection in children, with varying utility based on age and clinical presentation.
- Urine bag specimens are noted as unreliable for diagnosing urinary tract infections due to high false-positive rates.
- Urine microscopy is vital for confirming dipstick findings, identifying hematuria, glomerular bleeding, inflammation, and bacteria, while culture interpretation depends on the collection method.
Impact:
- Improved accuracy in diagnosing pediatric urinary tract infections and kidney conditions.
- Reduced misdiagnosis and unnecessary treatments due to unreliable specimen collection methods.
- Enhanced clinical decision-making through standardized interpretation of pediatric urinalysis.
Abstract:
The examination of urine in children can be very complex, due to the difficulty to obtain clean urine specimens in infants and toddlers. Clean catch is an easy system to obtain urine but patience is needed. Transurethral catheterization or suprapubic aspiration is useful in infants and toddlers with sign of pyelonephritis. Urine bag specimens are not useful in the diagnosis of urinary tract infection because of the high rate of false positive cultures. The 24 hours urine collection is frequently replaced by a spot urine and the ratio of the measured substances with the urine creatinine are calculated. Urine microscopy is needed for the evaluation of pathological results in the dipstick testing: confirm that red urine is due to haematuria by demonstration of red blood cells on urine microscopy, dysmorphic cells and red-cell casts are pathognomonic of glomerular bleeding, white-cell casts signify glomerular inflammation and bacteria are easily seen in unstained urine. A urine culture is pathologic if the colony count exceeds 10(4) in the transurethral catheterization or clean void. In the suprapubic aspiration is any number of colony pathologic. Urate crystals in the urine of infants may cause a pink discoloration to nappies. Urine screenings are not very useful and should be performed only at the age of 5 years or by sexual-active adolescents.
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