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Updated: Jul 19, 2026

A Generalized Method for Determining Free Soluble Phenolic Acid Composition and Antioxidant Capacity of Cereals and Legumes
Published on: June 10, 2022
[Determination of safflor yellow A by RP-HPLC and resources quality comparison in Carthamus tinctorius]
Mei-li Guo1, Ge Zhang, Wei Zhang
1College of Pharmacy, Second Military Medical University, Shanghai, China. mlguo@smmu.edu.cn
Objective:
To provide the basis for establishing evaluation criterion, selecting good strains and carring out good agricultural practice of the crude drug.
Method:
Representative 22 varieties of Carthamus tinctorius were selected and cultivated in different ecological localities and different years. And the content of safflor yellow A in their corollas were measured by RP-HPLC to compare the differences and their genetic stabilities among varieties.
Result:
The range of of safflor yellow A content was 0.70%-1.85% which were varied among varieties (P < 0.01). The content of safflor yellow A in varieties Yutai Honghua, Hefei Honghua, Rucheng Honghua were higher than in others.
Conclusion:
The effective compound safflor yellow A in C. tinctorius was one of the main quality evaluation criterions. Varieties Yutai Honghua, Hefei Honghua and Rucheng Honghua were good resources.